Researchers Explore Melt Electrospinning & 3D Printed Scaffolds for Guided Bone Regeneration2/26/2019 Researchers Explore Melt Electrospinning & 3D Printed Scaffolds for Guided Bone Regeneration https://ift.tt/2IDau8d Recent research by scientists at University Hospital Würzburg yields new insight into the uses of 3D printing in creating scaffolding for oral bone regeneration, offering results in ‘Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration – a pilot study in vitro.’ The use of scaffolds has been rife with challenges, and especially in guided bone regeneration (GBR). Problems include issues with handling in clinical environments, erratic degradation, lack of stability in cell growth, and more. The researchers in this case embarked on a study of scaffolds created through melt electrospinning writing (MEW) and consequent 3D printing, creating complex scaffold geometrics that can be fabricated specifically to bone tissue requirements—usually in maxillofacial applications.
Electrospinning offers a comparatively easy way to make scaffolds necessary to biomedical applications, employing a charged polymer jet pushed out from a spinneret and ‘drawn’ toward an area well fibers begin to form into a structure. For creating polymers, both solution electrospinning and MEW are used. MEW allows the operator to place fibers exactly, and without chemicals and solvents, meaning there is also no potential for solvents to be left in the scaffold.
All scaffolds for the study were made of medical-grade PCL and the researchers were able to use a MEW device that was customized by the Department for Functional Materials in Medicine and Dentistry Würzburg University Hospital. Cells were assessed and quantified, and then washed, sealed, and neutralized. Testing revealed good viability and proliferation.
End results showed not only good viability but also protein concentration, and cell number.
3D printing has lent so much to the world of innovation, from aerospace to fashion and beyond, but this technology has had significant impacts in medicine, and in areas that are vital but that many of us rarely think about or even know about, such as scaffolding. What do you think of this news? Let us know your thoughts! Join the discussion of this and other 3D printing topics at 3DPrintBoard.com. [Source / Images: Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration – a pilot study in vitro]
Printing via 3DPrint.com | The Voice of 3D Printing / Additive Manufacturing https://3dprint.com February 26, 2019 at 01:24AM
0 Comments
Leave a Reply. |
Categories
All
Archives
April 2023
|